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ea0011p791 | Thyroid | ECE2006

Loss of heterozygosity and genetic association analyses within 11q13.5-q14 chromosomal region in papillary thyroid carcinoma

Ramirez-Lorca R , Ferrero Herrero E , Saez ME , Labalde Martinez M , Real LM , Ruiz A , Hidalgo Pascual M

Introduction: Papillary Thyroid cancer (PTC) accounts for 80% or more of all thyroid malignancies and genetic alterations associated with the development and progresion of this type of carcinoma remains largely unknown. Chromosomal band 11q13 seems to be one of the most frequently amplified regions in human cancer. Allelic imbalance involving EMSY, CAPN5 and PAK1 loci in thyroid cancer, have never been investigated. The aim of our study was to investigate the existence of alle...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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